CELEBREX should never be used right before or after a heart surgery called “coronary artery bypass graft” (CABG). Avoid taking NSAIDs after a recent heart attack, unless your healthcare provider tells you to do so. You may have an increased risk of another heart attack if you take NSAIDs after a recent heart attack. NSAID medications, like CELEBREX, cause an increased risk of bleeding. El celecoxib es un medicamento antiinflamatorio no esteroideo (AINE) indicado para el alivio del dolor en pacientes con osteoartritis, dismenorrea y artritis reumatoide, aunque también es utilizado para el alivio de los síntomas en pacientes mayores de dos años que sufran artritis reumatoide juvenil.Se vende con diferentes nombres comerciales, entre otros «Celebrex». [2] Aleve (naproxen) and Celebrex (celecoxib), a COX-2 inhibitor, are types of nonsteroidal anti-inflammatory drugs (NSAIDs) that block your body from producing certain natural hormones that cause inflammation. Celebrex causes less inflammation and ulcers of the digestive tract than do other NSAIDs. Aleve and Celebrex both treat pain and inflammation caused by many conditions. But the decision appeared to make it likely that Celebrex will be the only Cox-2 drug available to U.S. patients. Regulators said that Pfizer would have to provide significant new data showing. CELEBREX is contraindicated in the setting of coronary artery bypass graft (CABG) surgery. [see CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS] Gastrointestinal Bleeding, Ulceration, and Perforation. NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, andperforation of the stomach or intestines, which can be fatal. These events can. Pourtant, ni le CELEBREX ni le VIOXX n’ont, dans les études cliniques soumises par leurs fabricants aux agences sanitaires, fait mieux que les médicaments existants à l’époque mais les experts européens et ceux de l’AFSSAPS pensent que ces nouveaux anti-inflammatoires entraînent moins d’effets indésirables digestifs « graves » que les anti-inflammatoires existants. Pour en.